Pharmacomicrobiomics: Another Contributor of Inter-Individual Variations To Drug Response

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Published

2022-10-31

DOI:

https://doi.org/10.55229/ijbs.v25i2.01

Keywords:

Pharmacomicrobiomics, psychotropics, antidepressants, gut-microbiota

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Authors

  • Adarsh Tripathi Professor, Department of Psychiatry, King Geroge’s medical University, Lucknow, Uttar Pradesh, India

Abstract

Gut-brain axis is now a commonly discussed concept in a variety of clinical contexts including its well-known importance in neuropsychiatric disorders. Gut microbiota is a diverse population of microorganisms containing bacteria, yeast, protozoa, parasite, helminth, viruses, etc.

How to Cite

Tripathi, A. (2022). Pharmacomicrobiomics: Another Contributor of Inter-Individual Variations To Drug Response. Indian Journal of Behavioural Sciences, 25(02), 78–79. https://doi.org/10.55229/ijbs.v25i2.01

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References

Reference:

Sender R, Fuchs S, Milo R. Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans. Cell. 2016 Jan;164(3):337–40.

Weersma RK, Zhernakova A, Fu J. Interaction between drugs and the gut microbiome. Gut. 2020 Aug 1;69(8):1510-9.

Kalow W, Tang B-K, Endrenyi L (1998) Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research. Pharmacogenetics 8:283–289

Hassan R, Allali I, Agamah FE, Elsheikh SS, Thomford NE, Dandara C, Chimusa ER. Drug response in association with pharmacogenomics and pharmacomicrobiomics: towards a better personalized medicine. Briefings in Bioinformatics. 2021 Jul;22(4):bbaa292.

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