Irritable Bowel syndrome and Psychiatric Comorbidities: A narrative review





Keywords: Irritable Bowel Disease, Psychiatric Co-morbidities, Gut-brain axis

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  • Ankita Saroj Department of Psychiatry, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Adarsh Tripathi Department of Psychiatry, King George’s Medical University, Lucknow, Uttar Pradesh, India
  • Sumit Rungta Department of Medical Gastroenterology, King George’s Medical University, Lucknow, Uttar Pradesh, India


Irritable bowel syndrome (IBS) is the most commonly diagnosed illness by gastroenterologists. These symptoms occur widely in the general population at all ages and in both sexes. The condition is a considerable health-care burden, accounting for approximately half of all referrals to gastrointestinal clinics. The prevalence of IBS varies according on geographic region, demographic, and diagnostic criteria employed. IBS pathogenesis is complicated and poorly understood. Gut microbiota, small intestinal bacterial overgrowth (SIBO), visceral hypersensitivity, disruption of the gut-brain axis, psychosocial distress, and altered GI motility all are proposed as potential risk factors. Inflammatory bowel syndrome (IBS) is associated with considerable psychosocial comorbidities, which have an impact on patient quality of life, disease progression, and health-care expenditures. The present article reviews the latest evidence on the aetiology IBS, with a focus on psychiatric comorbidities and available management available.

How to Cite

Ankita Saroj, Adarsh Tripathi, & Rungta, S. (2022). Irritable Bowel syndrome and Psychiatric Comorbidities: A narrative review. Indian Journal of Behavioural Sciences, 25(02), 106–116.


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Author Biographies

Adarsh Tripathi, Department of Psychiatry, King George’s Medical University, Lucknow, Uttar Pradesh, India

Professor, Department of Psychiatry, King George’s Medical University, Lucknow, U.P.

Sumit Rungta, Department of Medical Gastroenterology, King George’s Medical University, Lucknow, Uttar Pradesh, India

Additional Professor & Head, Department of Medical Gastroenterology, King George’s Medical University, Lucknow, U.P.



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Table 1. Rome IV Criteria* For Diagnosis Irritable Bowel Syndrome*

Table 2. Diagnostic Criteria For IBS subtypes*

*Adapted from

Table 3. Treatment modalities

Adapted from Videlock EJ, Chang L. Irritable bowel syndrome: current approach to symptoms, evaluation, and treatment. Gastroenterology Clinics of North America. 2007 Sep 1;36(3):665-85.